Introduction
Background
Traditionally, monitoring column integrity in chromatography has relied on the pulse injection method, but its impracticality throughout a column's lifetime is evident due to added processing, material costs, and disruptions to manufacturing schedules. Enter Chromatography Transition Analysis (ChromTA), a game-changer utilizing routine manufacturing in-process data. By leveraging conductivity shifts during buffer transitions, ChromTA provides insights into dispersion characteristics, offering a novel approach to gauge column performance. Furthermore, Statistical Process Control (SPC) techniques enhance analysis by detecting trends in output parameters. Welcome to a new era of efficient column monitoring and enhanced manufacturing processes!
More Information
For a comprehensive overview of the capabilities offered by the ChromTA module, please visit open-dcp.ai.